How does breast cancer form in cells?
Abigail Rogers
Updated on February 27, 2026
Doctors know that breast cancer occurs when some breast cells begin to grow abnormally. These cells divide more rapidly than healthy cells do and continue to accumulate, forming a lump or mass. Cells may spread (metastasize) through your breast to your lymph nodes or to other parts of your body.
What cell types does breast cancer usually arise?
All breast carcinomas arise from the epithelial cells in the terminal duct lobular unit. A disease that widely affects the entire body. A treatment that can reach cancer cells that have potentially spread throughout the body.
What is the most common route of metastasis for breast cancer?
Metastasis or tumor cell dissemination occurs via the hematogenous and lymphatic systems. For many carcinomas, the dissemination of tumor cells via lymphatic drainage of the tumor is the most common metastatic route.
How do normal breast cells become cancerous?
Normal breast cells become cancer because of changes (mutations) in DNA. DNA is the chemical in our cells that makes up our genes. Genes have the instructions for how our cells function. Some DNA mutations are inherited or passed to you from your parents.
What is breasts cancer?
Breast cancer is a disease in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast.
What happens when breast cancer spreads outside the breast?
The cancer cells grow outside the ducts into other parts of the breast tissue. Invasive cancer cells can also spread, or metastasize, to other parts of the body.
What is an epithelial cancer of the breast?
Carcinomas are cancers that arise from the epithelial component of the breast. The epithelial component consists of the cells that line the lobules and terminal ducts; under normal conditions, these epithelial cells are responsible for making milk.