What are the bad side effects of glipizide?
Mia Phillips
Updated on February 26, 2026
Nausea, vomiting, loss of appetite, diarrhea, constipation, upset stomach, headache, and weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What should you avoid when taking glipizide?
Extended-release glipizide tablets should be taken with the first meal of the day. Glipizide should never be taken with alcohol, and most doctors will recommend trying to avoid alcohol as much as possible while taking the medication. Consuming alcohol while taking glipizide can cause severe hypoglycemia.
What happens if you don’t eat after taking glipizide?
If you do not eat within 30 minutes of taking glipizide IR tablets or do not eat a meal with glipizide ER tablets, your blood sugar may drop too low. This increases your risk of hypoglycemia (low blood sugar). In some cases, hypoglycemia can become serious and may require urgent treatment.
Is glipizide a high risk medication?
In contrast, glipizide was associated with a 41 percent, and glyburide with a 38 percent greater risk. “Since many patients with type 2 diabetes also have coronary artery disease, our results could potentially impact the care of a large number of patients,” Pantalone said.
What is considered a high A1c?
For people without diabetes, the normal range for the hemoglobin A1c level is between 4% and 5.6%. Hemoglobin A1c levels between 5.7% and 6.4% mean you have prediabetes and a higher chance of getting diabetes. Levels of 6.5% or higher mean you have diabetes.
What are the long term effects of glipizide?
Incidence Not Known. Agitation. back or leg pains. bleeding gums. blood in the urine or stools. chest pain. convulsions. decreased urine output.
What are the sexual side affects of glipizide?
Decreased interest in sexual intercourse
When should I take Glipizide?
Take glipizide tablets about half an hour before a meal (usually breakfast). Remember to follow any advice you have been given about what you should or shouldn’t eat, and try to take some regular exercise. Make sure you know how to recognise the symptoms of low blood sugar.
Does Glipizide cause weight gain?
Glipizide is one of several drugs used to treat the disease, but many patients can gain weight from using it, which is not a good situation for diabetics. Healthy diet and exercise are advised to fight the possible weight gain from this drug. Eat a healthy diet. MayoClinic.com says a “diabetes diet” is a myth.