What are three diseases that can affect the lymphatic system including mononucleosis?
Isabella Ramos
Updated on May 03, 2026
Burkitt’s lymphoma (cancer of the lymphatic system)
What viruses affect the lymphatic system?
Viral Diseases of the Circulatory and Lymphatic Systems
| Table 1. Viral Diseases of the Circulatory and Lymphatic Systems | |
|---|---|
| Disease | Pathogen |
| AIDS/HIV infection | Human immunodeficiency virus (HIV) |
| Burkitt lymphoma | Epstein-Barr virus (human herpesvirus-4 [HHV-4]) |
| Chikungunya fever | Chikungunya virus |
Does mononucleosis cause joint pain?
Mono usually is not serious, but some people with mono feel very tired and have pain in their joints that lasts for several weeks.
How does lymphadenitis affect the lymphatic system?
Lymphadenitis is an infection in one or more lymph nodes. When lymph nodes become infected, it’s usually because an infection started somewhere else in your body. Lymphadenitis can cause lymph nodes to become enlarged, red, or tender. Treatment may include antibiotics, and medications to control pain and fever.
How do you know if you have EBV?
Symptoms
- fatigue.
- fever.
- inflamed throat.
- swollen lymph nodes in the neck.
- enlarged spleen.
- swollen liver.
- rash.
What are the signs and symptoms of infectious mononucleosis?
Typical symptoms of infectious mononucleosis include—. extreme fatigue. fever. sore throat. head and body aches. swollen lymph nodes in the neck and armpits. swollen liver or spleen or both. rash.
How do you know if you have mono?
You might feel more tired than usual and have a mild fever and sore throat. Your lymph nodes, tissue that normally acts as filters, may swell under your arms and in your neck and groin area. You also may have body aches and pains, swollen tonsils, headache, and even a skin rash. Who Gets It? Anyone can get mono.
What are the side effects of Mono?
Mono can inflame your liver and cause jaundice that yellows your skin and the whites of your eyes. Less often, it can inflame the heart muscle (myocarditis), cause clotting problems, infect the nervous system (meningitis, Guillain-Barre), and make your red blood cells drop (anemia).
Can EBV cause infectious mononucleosis (mono)?
EBV can cause infectious mononucleosis, also called mono, and other illnesses. Most people will get infected with EBV in their lifetime and will not have any symptoms.
