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The Daily Insight

What is the difference between spondylitis and spondyloarthritis?

Author

Christopher Pierce

Updated on March 01, 2026

Spondylitis occurs due to inflammation that causes arthritis while spondylosis is wear and tear of the vertebrae that results in disk and joint degeneration. Spondylosis and spondylitis are both conditions of the joints in your spine.

Is Spondyloarthritis serious?

Like many other chronic conditions, spondyloarthritis symptoms may come and go. Symptoms may also vary from day to day. Complications, such as heart problems and lung scarring due to long-term inflammation, are rare. Spondyloarthritis is serious.

How common is axSpA?

Around 5.5 million Americans have axial spondyloarthritis (axSpA), an inflammatory form of arthritis that is associated with chronic lower back pain.

What does spondyloarthritis feel like?

Symptoms. For many people, the first and predominant symptom of spondyloarthritis is pain in the lower back and hips, especially in the morning and after periods of inactivity. But pain and swelling can also occur in shoulders, hips, knees, ankles and hands. It can range from mild to severe.

Does spondyloarthritis make you tired?

While fatigue is not unique to spondyloarthritis, it is a rather common symptom of it, and one that doesn’t often receive the attention it deserves. Fatigue can negatively impact one’s work, social life, relationships, ability to focus, and even emotional state.

How can I treat spondyloarthritis at home?

These 10 natural therapies may help relieve symptoms:

  1. Stretching. Stretching helps build flexibility and may reduce pain.
  2. Heat therapy. To reduce stiffness and pain, apply a hot-water bottle or heating pad to the affected area.
  3. Cold therapy.
  4. Acupuncture.
  5. Massage therapy.
  6. Movement.
  7. Exercise.
  8. Alexander Technique.

What causes axSpA?

The disease can be more common in certain families. For example, a person’s risk of developing axSpA increases if a first-degree relative (parent, sibling, or child) has axSpA. The presence of a gene called human leukocyte antigen (HLA) B27 also increases the risk of developing axSpA.

Is NR-axSpA an autoimmune disease?

Nr-AxSpA is a cross between an auto-inflammatory and autoimmune condition. The immune system gets confused and thinks the body is being attacked. As the body produces inflammation to protect against the non-existent attacker, healthy tissue is damaged in the process.

What is axaxial spondyloarthritis (axSpA)?

Axial Spondyloarthritis – also known as axSpA or axial SpA – is a painful, chronic arthritis that mainly affects the joints of the spine. It can also affect other joints in the body, as well as tendons and ligaments.

What does R-axSpA mean on Xray?

If arthritis of the sacroiliac joints (pelvis) or spine can be seen on x-ray, the term used is radiographic axial Spondyloarthritis (r-axSpA). This condition was previously called Ankylosing Spondylitis (AS) and today, both terms (r-axSpA and AS) are used interchangeably.

What are the treatment options for axial sphincter atrophy ( axSpA)?

Therefore, NSAIDs, unless contraindicated, are the treatment of choice for the majority of patients with axSpA. Beyond NSAIDs, only tumour necrosis factor (TNF) α blockers are effective and approved for the treatment of active axSpA.

What are the differences between patients with rheumatoid arthritis (RA) and Nr axSpA?

The level of disease activity, pain measures, and functional impairment are similar, whereas patients with nr axSpA are more likely to be female (2:1 male: female r axSpA vs 1:1 ratio in nr axSpA), demonstrate lower C reactive protein levels, and, by definition, show less structural damage. Both groups respond equally to biologic agents.